Tani waa qayb ka mid ah taxanahayaga socda ee ka caawinaya macaamiisha si fiican u fahmaan maaddooyinka dawooyinka.Waanu turjunnaa cilmiga dawooyinka, waxaanu sharaxnaa dabeecadaha daroogooyinka, waxaanu ku siinaa talo daacad ah, si aad u doorato daawooyinka saxda ah ee qoyskaaga!

Qaaciddada molecular ee Zolmitriptan: C16H21N3O2

Kiimikada IUPAC Magaca: (S)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-hal

CAS No.: 139264-17-8

Qaab-dhismeedka:

Zolmitriptan

Zolmitriptan waa agonist receptor serotonin oo la xushay oo ka mid ah noocyada 1B iyo 1D.Waa triptan, oo loo isticmaalo daawaynta degdega ah ee werarrada dhanjafka oo leh ama aan lahayn aura iyo madax-xanuun kooxeed.Zolmitriptan waa derivative tryptamine synthetic oo u muuqda sida budo cad oo qayb ahaan ku milmay biyaha.

Zomig waa serotonin (5-HT) agonist receptor ah oo loo isticmaalo daawaynta dhanjafka daran ee dadka waaweyn.Walaxda firfircoon ee Zomig waa zolmitriptan, oo ah agonist receptor serotonin xulashada.Waxaa loo kala saaraa sida triptan, kaas oo la aaminsan yahay inuu yareeyo xanuunka dhanjafka isagoo yareynaya bararka iyo cidhiidhiga xididdada dhiigga.Sida xulashada serotonin agonist receptor, Zomig wuxuu kaloo joojiyaa calaamadaha xanuunka loo diro maskaxda wuxuuna xannibaa sii deynta kiimikooyinka qaarkood ee jirka ku jira ee keena calaamadaha xanuunka dhanjafka, oo ay ku jiraan madax xanuun, lallabbo, iyo dareenka iftiinka iyo dhawaaqa.Zomig waxaa lagu tilmaamaa madax xanuunka dhanjafka leh ama aan lahayn aura, calaamadaha muuqaalka ama dareenka dadka qaarkiis oo qaba madax xanuunka ka hor.

Isticmaalka Zolmitriptan

Zolmitriptan waxaa loo isticmaalaa daawaynta degdega ah ee dhanjafka leh ama aan lahayn aura ee dadka waaweyn.Zolmitriptan looguma talagalin daawaynta kahortaga xanuunka dhanjafka ama in loo isticmaalo maaraynta dhanjafka hemiplegic ama basilar.

Zolmitriptan waxa loo heli karaa kaniini la liqi karo, kiniin afka laga qaato, iyo buufin sanka lagu buufiyo, qiyaas ahaan 2.5 iyo 5 mg.Dadka uu xanuunka dhanjafku ka qaado aspartame waa in aanay isticmaalin kiniinka burburaya (Zomig ZMT), kaas oo ka kooban aspartame.

Marka loo eego daraasad lagu sameeyay tabaruceyaal caafimaad qaba, qaadashada cunnada waxay u muuqataa inaysan saameyn weyn ku yeelan waxtarka Zolmitriptan ee ragga iyo dumarka labadaba.

Zolmitriptan-ka ku jira Zomig wuxuu ku xidhaa qaar ka mid ah soo-qabayaasha serotonin.Cilmi-baadhayaashu waxay aaminsan yihiin in Zomig uu u shaqeeyo isagoo ku xiraya soo-dhoweeyayaasha neurons (unugyada dareemayaasha) iyo xididdada dhiigga ee maskaxda, taasoo keenta xididdada dhiigga inay ciriiriyaan oo joojiyaan kiimikooyinka kordhin doona caabuqa.Zomig wuxuu kaloo yareeyaa walxaha keena xanuunka madaxa oo laga yaabo inay ku lug yeeshaan calaamadaha kale ee caadiga ah ee xanuunka dhanjafka, sida lallabbo, dareenka iftiinka, iyo dareenka codka.Zomig wuxuu si fiican u shaqeeyaa marka la qaato calaamadda ugu horreysa ee xanuunka dhanjafka.Ma ka hortagto xanuunka dhanjafka ama ma dhimayso tirada weerarrada madax xanuunka ee aad qabto.

Saamaynta ay leedahay Zolmitriptan

Sida dawooyinka oo dhan, Zomig waxa laga yaabaa inuu keeno waxyeelo aan loo baahnayn.Dhibaatooyinka ugu badan ee ay la kulmaan dadka qaata kiniiniyada Zomig waa xanuun, cidhiidhi ama cadaadis qoorta, cunaha, ama daanka;dawakhaad, xiirid, daciifnimo ama tamar la'aan, hurdo la'aan, dareen diirimaad ama qabow, lallabbo, dareen culus, iyo af qallayl.Dhibaatooyinka ugu badan ee ay la kulmaan dadka qaata buufinta sanka ee Zomig waa dhadhan aan caadi ahayn, xiirid, dawakhaad, iyo dareenka maqaarka, gaar ahaan maqaarka ku wareegsan sanka.

Tixraacyo

https://en.wikipedia.org/wiki/Zolmitriptan

https://www.ncbi.nlm.nih.gov/pubmed/16412157

https://www.ncbi.nlm.nih.gov/pubmed/18788838

https://www.ncbi.nlm.nih.gov/m/pubmed/10473025

Maqaallada La Xiriira

Ramipril wuxuu caawiyaa Cadaadiska Dhiigga Hoose

Ku dawee cudurka sokorowga nooca 2 ee Linagliptin

Raloxifene waxay ka hortagtaa lafo-jileecu waxayna yaraynaysaa halista kansarka naasaha ee faafa