He ʻāpana kēia o kā mākou pūʻulu hoʻomau e kōkua ana i nā mea kūʻai aku e hoʻomaopopo maikaʻi i nā mea lāʻau lapaʻau.Unuhi mākou i ka ʻepekema lāʻau lapaʻau, wehewehe i nā ʻano lāʻau lapaʻau, a hāʻawi iā ʻoe i ka ʻōlelo aʻo pololei, no laila hiki iā ʻoe ke koho i nā lāʻau kūpono no kou ʻohana!
ʻO ke kumu molekala o Zolmitriptan: C16H21N3O2
IUPAC Inoa: (S)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
Helu CAS: 139264-17-8
Hui Pū ʻIa:
ʻO Zolmitriptan
ʻO Zolmitriptan kahi agonist receptor serotonin koho o nā subtypes 1B a me 1D.He triptan ia, i hoʻohana ʻia i ka mālama ʻana i nā hōʻeha o ka migraine me ka ʻole a i ʻole aura a me nā poʻo poʻo.ʻO Zolmitriptan kahi mea hana tryptamine derivative a ʻike ʻia e like me ka pauka keʻokeʻo i hiki ke hoʻoheheʻe ʻia i ka wai.
ʻO Zomig kahi serotonin (5-HT) receptor agonist i hoʻohana ʻia i ka mālama ʻana i nā migraines koʻikoʻi i nā pākeke.ʻO ka mea hana ma Zomig ʻo zolmitriptan, kahi agonist receptor serotonin koho.Hoʻokaʻawale ʻia ʻo ia ma ke ʻano he triptan, i manaʻo ʻia e hōʻemi i ka ʻeha o ka migraine ma o ka hoʻomaha ʻana i ka pehu a me ka hōʻemi ʻana i nā kīʻaha koko.Ma ke ʻano he serotonin receptor agonist koho, hoʻōki pū ʻo Zomig i nā hōʻailona ʻeha e hoʻouna ʻia i ka lolo a pale i ka hoʻokuʻu ʻana o kekahi mau mea kemika i loko o ke kino e hōʻeha ai i nā hōʻailona o ka migraine, me ka ʻeha o ke poʻo, nausea, a me ka naʻau i ka mālamalama a me ke kani.Hōʻike ʻia ʻo Zomig no ka migraines me ka aura a ʻaʻole paha, nā hōʻailona ʻike a i ʻole nā hōʻailona i ʻike ʻia e kekahi poʻe me ka migraine ma mua o ka ʻeha poʻo.
ʻO ka hoʻohana ʻana o Zolmitriptan
Hoʻohana ʻia ʻo Zolmitriptan no ka mālama koʻikoʻi o ka migraines me ka ʻole o ka aura i nā pākeke.ʻAʻole i manaʻo ʻia ʻo Zolmitriptan no ka prophylactic therapy o ka migraine a i ʻole no ka hoʻohana ʻana i ka mālama ʻana i ka hemiplegic a i ʻole basilar migraine.
Loaʻa ka Zolmitriptan ma ke ʻano he papa hiki ke ʻai ʻia, kahi papa hoʻoheheʻe waha, a me kahi ʻūhā ihu, ma nā ʻano o 2.5 a me 5 mg.ʻAʻole pono ka poʻe i loaʻa i ka migraines mai ka aspartame i ka papa disintegrating (Zomig ZMT), aia ka aspartame.
Wahi a kahi noiʻi o nā limahana olakino, ʻaʻohe hopena koʻikoʻi o ka ʻai ʻana i ka hopena o Zolmitriptan i nā kāne a me nā wahine.
Hoʻopili ka zolmitriptan i Zomig i kekahi mau mea hoʻokipa serotonin.Manaʻo ka poʻe noiʻi e hana ana ʻo Zomig ma ka hoʻopaʻa ʻana i kēia mau mea loaʻa i loko o nā neurons (nā pūnaewele nerve) a ma nā kīʻaha koko i loko o ka lolo, e hoʻopaʻa ai nā kīʻaha koko a keʻakeʻa nei i nā kemika e hoʻonui ai i ka mumū.Hoʻemi pū ʻo Zomig i nā mea e hoʻoulu ai i ka ʻeha poʻo a pili paha i nā hōʻailona maʻamau ʻē aʻe o ka migraine, e like me ka nausea, ka naʻau i ka mālamalama, a me ke kani.Hana maikaʻi ʻo Zomig i ka wā e lawe ʻia ai i ka hōʻailona mua o kahi migraine.ʻAʻole ia e pale i ka migraine a i ʻole e hōʻemi i ka nui o nā hōʻeha migraine i loaʻa iā ʻoe.
Nā hopena ʻaoʻao o Zolmitriptan
E like me nā lāʻau lapaʻau a pau, hiki i Zomig ke hana i nā hopena ʻaoʻao i manaʻo ʻole ʻia.ʻO nā hopena ʻaoʻao maʻamau i ʻike ʻia e ka poʻe e lawe ana i nā papa Zomig he ʻeha, paʻa a i ʻole ke kaomi ʻana i ka ʻāʻī, ka ʻāʻī, a i ʻole ka ʻāwae;ʻūlū, ʻūlū, nāwaliwali a nele paha i ka ikehu, hiamoe, manaʻo mehana a i ʻole ke anu, nausea, ke kaumaha a me ka waha maloʻo.ʻO nā hopena ʻaoʻao maʻamau i ʻike ʻia e ka poʻe e lawe ana i ka Zomig nasal spray he ʻono ʻokoʻa, ʻūlū, ʻūlū, a me ka naʻau o ka ʻili, ʻoi aku ka ʻili a puni ka ihu.
Nā kuhikuhi
https://en.wikipedia.org/wiki/Zolmitriptan
https://www.ncbi.nlm.nih.gov/pubmed/16412157
https://www.ncbi.nlm.nih.gov/pubmed/18788838
https://www.ncbi.nlm.nih.gov/m/pubmed/10473025
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Ka manawa hoʻouna: Apr-30-2020